Ontology highlight
ABSTRACT:
SUBMITTER: Kim JS
PROVIDER: S-EPMC2783391 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Kim Jong-So JS Bailey Michael J MJ Weller Joan L JL Sugden David D Rath Martin F MF Møller Morten M Klein David C DC
Molecular and cellular endocrinology 20090529 1
Dopamine plays diverse and important roles in vertebrate biology, impacting behavior and physiology through actions mediated by specific G-protein-coupled receptors, one of which is the dopamine receptor D4 (Drd4). Here we present studies on the >100-fold daily rhythm in rat pineal Drd4 expression. Our studies indicate that Drd4 is the dominant dopamine receptor gene expressed in the pineal gland. The gene is expressed in pinealocytes at levels which are approximately 100-fold greater than in ot ...[more]