Ontology highlight
ABSTRACT:
SUBMITTER: Vecsey CG
PROVIDER: S-EPMC2783639 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Vecsey Christopher G CG Baillie George S GS Jaganath Devan D Havekes Robbert R Daniels Andrew A Wimmer Mathieu M Huang Ted T Brown Kim M KM Li Xiang-Yao XY Descalzi Giannina G Kim Susan S SS Chen Tao T Shang Yu-Ze YZ Zhuo Min M Houslay Miles D MD Abel Ted T
Nature 20091001 7267
Millions of people regularly obtain insufficient sleep. Given the effect of sleep deprivation on our lives, understanding the cellular and molecular pathways affected by sleep deprivation is clearly of social and clinical importance. One of the major effects of sleep deprivation on the brain is to produce memory deficits in learning models that are dependent on the hippocampus. Here we have identified a molecular mechanism by which brief sleep deprivation alters hippocampal function. Sleep depri ...[more]