Ontology highlight
ABSTRACT:
SUBMITTER: Li Q
PROVIDER: S-EPMC2785041 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Li Qingsheng Q Estes Jacob D JD Schlievert Patrick M PM Duan Lijie L Brosnahan Amanda J AJ Southern Peter J PJ Reilly Cavan S CS Peterson Marnie L ML Schultz-Darken Nancy N Brunner Kevin G KG Nephew Karla R KR Pambuccian Stefan S Lifson Jeffrey D JD Carlis John V JV Haase Ashley T AT
Nature 20090304 7241
Although there has been great progress in treating human immunodeficiency virus 1 (HIV-1) infection, preventing transmission has thus far proven an elusive goal. Indeed, recent trials of a candidate vaccine and microbicide have been disappointing, both for want of efficacy and concerns about increased rates of transmission. Nonetheless, studies of vaginal transmission in the simian immunodeficiency virus (SIV)-rhesus macaque (Macacca mulatta) model point to opportunities at the earliest stages o ...[more]