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Draft genome sequences of Yersinia pestis isolates from natural foci of endemic plague in China.

ABSTRACT: To gain insights into the evolutionary origin, emergence, and pathogenicity of the etiologic agent of plague, we have sequenced the genomes of four Yersinia pestis strains isolated from the zoonotic rodent reservoir in foci of endemic plague in China. These resources enable in-depth studies of Y. pestis sequence variations and detailed whole-genome comparisons of very closely related genomes from the supposed site of the origin and the emergence of global pandemics of plague.

SUBMITTER: Eppinger M

PROVIDER: S-EPMC2786597 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature

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Draft genome sequences of Yersinia pestis isolates from natural foci of endemic plague in China.

Eppinger Mark M Guo Zhaobiao Z Sebastian Yinong Y Song Yajun Y Lindler Luther E LE Yang Ruifu R Ravel Jacques J

Journal of bacteriology 20091009 24

To gain insights into the evolutionary origin, emergence, and pathogenicity of the etiologic agent of plague, we have sequenced the genomes of four Yersinia pestis strains isolated from the zoonotic rodent reservoir in foci of endemic plague in China. These resources enable in-depth studies of Y. pestis sequence variations and detailed whole-genome comparisons of very closely related genomes from the supposed site of the origin and the emergence of global pandemics of plague. ...[more]

PMID: 19820101

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