Ontology highlight
ABSTRACT:
SUBMITTER: Ammerman NC
PROVIDER: S-EPMC2786609 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Ammerman Nicole C NC Gillespie Joseph J JJ Neuwald Andrew F AF Sobral Bruno W BW Azad Abdu F AF
Journal of bacteriology 20091009 24
Phylogenomics reveals extreme gene loss in typhus group (TG) rickettsiae relative to the levels for other rickettsial lineages. We report here a curious protease-encoding gene (ppcE) that is conserved only in TG rickettsiae. As a possible determinant of host pathogenicity, ppcE warrants consideration in the development of therapeutics against epidemic and murine typhus. ...[more]