Improved method for the synthesis of beta-carbonyl silyl-1,3-dithianes by the double conjugate addition of 1,3-dithiol to propargylic carbonyl compounds.

ABSTRACT: Base-mediated double conjugate addition of 1,3-propane dithiol to various silylated propargylic aldehydes and ketones allows for an efficient and scalable synthesis of beta-carbonyl silyl-1,3-dithianes.

SUBMITTER: Mukherjee S 

PROVIDER: S-EPMC2787704 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature