Ontology highlight
ABSTRACT:
SUBMITTER: Sakugawa N
PROVIDER: S-EPMC2788684 | biostudies-literature | 2009 Sep-Oct
REPOSITORIES: biostudies-literature
Sakugawa Naoko N Miyamoto Toshinobu T Tsujimura Akira A Koh Eitetsu E Miyagawa Yasushi Y Sato Hisashi H Namiki Mikio M Okuyama Akihiko A Sengoku Kazuo K
Journal of assisted reproduction and genetics 20090901 9-10
<h4>Purpose</h4>To investigate whether the human LMTK2 and PARP-2 gene defects are associated with azoospermia by meiotic arrest, mutational analysis was performed on Japanese men with azoospermia.<h4>Methods</h4>Via direct sequencing, mutational screening was carried out on the exon region of the genes, using genomic DNAs from 18 Japanese men. Statistical analysis was done on the detected single nucleotide polymorphisms (SNPs) in the patients and normal controls.<h4>Results</h4>Nine SNPs were d ...[more]