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Comparison of maternal and newborn outcomes of Tibetan and Han Chinese delivering in Lhasa, Tibet.

ABSTRACT: AIM:To compare maternal and neonatal outcomes of Tibetan and Han Chinese women delivering vaginally at high altitude (3650 meters) in Lhasa, Tibet Autonomous Region, People's Republic of China. METHOD:Comparative analysis of data from a prospective observational study of Tibetan (n = 938) and Han Chinese (n = 146) women delivering at three hospitals between January 2004 and May 2005. RESULTS:Han Chinese women had higher rates of pre-eclampsia/gestational hypertension than Tibetan women, (10.3% vs 5.9%, P = 0.04). There was no difference in rates of postpartum hemorrhage between Tibetan and Han women (12.8% vs 17.1%, P = 0.15). Han newborns weighed significantly less than Tibetan newborns (P < 0.01), and were twice as likely to be small for gestational age, (24.5% vs 11.6%, P < 0.01). Tibetan newborns were less likely to have poor neonatal outcomes than Han newborns (P < 0.01). CONCLUSION:In high altitude deliveries in Tibet, adverse outcomes were significantly more common among Han Chinese.

SUBMITTER: Miller S

PROVIDER: S-EPMC2789738 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature

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Comparison of maternal and newborn outcomes of Tibetan and Han Chinese delivering in Lhasa, Tibet.

Miller Suellen S Tudor Carrie C Thorsten Vanessa V Wright Linda L Varner Michael M

The journal of obstetrics and gynaecology research 20081201 6

<h4>Aim</h4>To compare maternal and neonatal outcomes of Tibetan and Han Chinese women delivering vaginally at high altitude (3650 meters) in Lhasa, Tibet Autonomous Region, People's Republic of China.<h4>Method</h4>Comparative analysis of data from a prospective observational study of Tibetan (n = 938) and Han Chinese (n = 146) women delivering at three hospitals between January 2004 and May 2005.<h4>Results</h4>Han Chinese women had higher rates of pre-eclampsia/gestational hypertension than T ...[more]

PMID: 19012697

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Project description:BackgroundTo estimate the prevalence of strabismus and associated risk factors among grade one school children in Lhasa, Tibet, China.MethodsThe Lhasa Childhood Eye Study (LCES) was a cross-sectional, school-based childhood study conducted in Grade one students from primary schools in Lhasa, Tibet, China. Comprehensive ophthalmic examinations and basic systemic examinations were evaluated. A questionnaire survey containing information about children, as well as parents' information, was sent to the corresponding parents of eligible children. The prevalence of strabismus and its 95% confidence interval was estimated. Univariate and multivariate logistic regression analyses were conducted to determine the associated risk factors.ResultsA total of 1942 eligible grade one students were enrolled, of which 1856 participants completed all examinations. The average age was 6.83 ± 0.46 years, 53% of participants were boys and 1762 were the Tibetan Minority. Over all, the prevalence of strabismus was 68/1856 (3.7%) (95%CI: 2.81,4.52), with no difference between the ages, genders, ethnicities and body mass index, while tilting one's head when writing may be a risk factor for strabismus (P = 0.004). Strabismus students had mean best corrected visual acuity of 0.16 ± 0.28(LogMAR), over 50% patients with esotropia were hyperopic, and participants who had stereopsis impairments showed a significant difference between esotropia and exotropia (P = 0.026).ConclusionsThe prevalence of strabismus in LCES was 3.7%, which is higher than previous reports from Chinese childhood epidemiology studies. Strabismus is a common contributing factor to amblyopia. Tilting one's head when writing may be a risk factor. Esotropia is more likely to affect stereopsis and be associated with the refractive state of hyperopia.Trial registrationThe study has finished the clinical registration on Chinese Clinical Trial Registry. ( http://www.chictr.org.cn , ChiCTR1900026693 ).

Dataset Information

Comparison of maternal and newborn outcomes of Tibetan and Han Chinese delivering in Lhasa, Tibet.

Publications

Comparison of maternal and newborn outcomes of Tibetan and Han Chinese delivering in Lhasa, Tibet.

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