Association of FGFR4 genetic polymorphisms with prostate cancer risk and prognosis.
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ABSTRACT:
SUBMITTER: FitzGerald LM
PROVIDER: S-EPMC2790323 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
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Association of FGFR4 genetic polymorphisms with prostate cancer risk and prognosis.
FitzGerald L M LM Karlins E E Karyadi D M DM Kwon E M EM Koopmeiners J S JS Stanford J L JL Ostrander E A EA
Prostate cancer and prostatic diseases 20080902 2
The fibroblast growth factor receptor 4 (FGFR4) is thought to be involved in many critical cellular processes and has been associated with prostate cancer risk. Four single nucleotide polymorphisms (SNPs) within or near FGFR4 were analyzed in a population-based study of 1458 prostate cancer patients and 1352 age-matched controls. We found no evidence to suggest that any of the FGFR4 SNP genotypes were associated with prostate cancer risk or with disease aggressiveness, Gleason score or stage. A ...[more]
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