Ontology highlight
ABSTRACT:
SUBMITTER: Schmitt JE
PROVIDER: S-EPMC2790393 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Schmitt J E JE Lenroot R K RK Wallace G L GL Ordaz S S Taylor K N KN Kabani N N Greenstein D D Lerch J P JP Kendler K S KS Neale M C MC Giedd J N JN
Cerebral cortex (New York, N.Y. : 1991) 20080129 8
Structural magnetic resonance imaging data from 308 twins, 64 singleton siblings of twins, and 228 singletons were analyzed using structural equation modeling and selected multivariate methods to identify genetically mediated intracortical associations. Principal components analyses (PCA) of the genetic correlation matrix indicated a single factor accounting for over 60% of the genetic variability in cortical thickness. When covaried for mean global cortical thickness, PCA, cluster analyses, and ...[more]