Ontology highlight
ABSTRACT:
SUBMITTER: Wu RY
PROVIDER: S-EPMC2792031 | biostudies-literature | 2003 May
REPOSITORIES: biostudies-literature
Wu Rui-ying RY Zhang Rong-guang RG Zagnitko Olga O Dementieva Irina I Maltzev Natalia N Watson James D JD Laskowski Roman R Gornicki Piotr P Joachimiak Andrzej A
The Journal of biological chemistry 20030320 22
The crystal structure of a SlyA transcriptional regulator at 1.6 A resolution is presented, and structural relationships between members of the MarR/SlyA family are discussed. The SlyA family, which includes SlyA, Rap, Hor, and RovA proteins, is widely distributed in bacterial and archaeal genomes. Current evidence suggests that SlyA-like factors act as repressors, activators, and modulators of gene transcription. These proteins have been shown to up-regulate the expression of molecular chaperon ...[more]