Ontology highlight
ABSTRACT:
SUBMITTER: Wu J
PROVIDER: S-EPMC2792727 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Wu Jun J Jeong Hye Kyoung HK Bulin Sarah Elizabeth SE Kwon Sung Won SW Park Jeong Hill JH Bezprozvanny Ilya I
Journal of neuroscience research 20090601 8
Ginseng, the root of Panax ginseng C.A. Meyer (Araliaceae), is a widely used herbal medicine. Ginsenosides, the active ingredients of ginseng, are the main components responsible for many beneficial actions of ginseng. In the present study, we tested 10 different ginsenosides in the previously developed in vitro Huntington's disease (HD) assay with primary medium spiny striatal neuronal cultures (MSN) from the YAC128 HD mouse model. We found that nanomolar concentrations of ginsenoside Rb1 and R ...[more]