Dose effects of dietary phytosterols on cholesterol metabolism: a controlled feeding study.

ABSTRACT:

Background

Phytosterol supplementation of 2 g/d is recommended by the National Cholesterol Education Program to reduce LDL cholesterol. However, the effects of different intakes of phytosterol on cholesterol metabolism are uncertain.

Objective

We evaluated the effects of 3 phytosterol intakes on whole-body cholesterol metabolism.

Design

In this placebo-controlled, crossover feeding trial, 18 adults received a phytosterol-deficient diet (50 mg phytosterols/2000 kcal) plus beverages supplemented with 0, 400, or 2000 mg phytosterols/d for 4 wk each, in random order. All meals were prepared in a metabolic kitchen; breakfast and dinner on weekdays were eaten on site. Primary outcomes were fecal cholesterol excretion and intestinal cholesterol absorption measured with stabl

SUBMITTER: Racette SB 

PROVIDER: S-EPMC2793103 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature