Ontology highlight
ABSTRACT:
SUBMITTER: Hutson MS
PROVIDER: S-EPMC2793361 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Hutson M Shane MS Veldhuis J J Ma Xiaoyan X Lynch Holley E HE Cranston P Graham PG Brodland G Wayne GW
Biophysical journal 20091201 12
Laser microsurgery and finite element modeling are used to determine the cell-level mechanics of the amnioserosa-a morphogenetically crucial epithelium on the dorsal surface of fruit fly embryos (Drosophila melanogaster). In the experiments, a tightly focused laser ablates a subcellular hole (1 microm in diameter) that passes clean through the epithelium. The surrounding cells recoil from the wound site with a large range of initial recoil velocities. These depend on the embryo's developmental s ...[more]