Ontology highlight
ABSTRACT:
SUBMITTER: Pankratz ND
PROVIDER: S-EPMC2795937 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
BMC proceedings 20091215
After performing a genome-wide association study, it is often difficult to know which regions to follow up, especially when no one marker reaches genome-wide significance. Researchers frequently focus on their top N findings, knowing that true associations may be buried deeper in the list. Others focus on genes or regions that have multiple markers showing evidence of association. However, these markers are often in high linkage disequilibrium with one another (r2 > 0.80), which indicates that t ...[more]