Transfer RNA processing in archaea: unusual pathways and enzymes.
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ABSTRACT:
SUBMITTER: Heinemann IU
PROVIDER: S-EPMC2796832 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Publications
Transfer RNA processing in archaea: unusual pathways and enzymes.
Heinemann Ilka U IU Söll Dieter D Randau Lennart L
FEBS letters 20100101 2
Transfer RNA (tRNA) molecules are highly conserved in length, sequence and structure in order to be functional in the ribosome. However, mostly in archaea, the short genes encoding tRNAs can be found disrupted, fragmented, with permutations or with non-functional mutations of conserved nucleotides. Here, we give an overview of recently discovered tRNA maturation pathways that require intricate processing steps to finally generate the standard tRNA from these unusual tRNA genes. ...[more]
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