Ontology highlight
ABSTRACT:
SUBMITTER: Tsironi EE
PROVIDER: S-EPMC2797043 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
Tsironi Evangelia E EE Pefkianaki Maria M Tsezou Aspasia A Kotoula Maria G MG Dardiotis Efthimios E Almpanidou Pavlina P Papathanasiou Afroditi A AA Rodopoulou Paraskevi P Chatzoulis Dimitrios Z DZ Hadjigeorgiou Georgios M GM
Molecular vision 20091225
<h4>Purpose</h4>To investigate possible genetic associations of matrix metalloproteinase-1 (MMP1) and MMP3 gene polymorphisms with exfoliation syndrome (XFS) with (XFS/+G) and without (XFS/-G) glaucoma in a cohort of Greek patients.<h4>Methods</h4>A total of 182 unrelated Greek patients with XFS, including 92 patients with XFS/+G, and 214 unrelated age- and gender-matched controls were enrolled in the study. MMP1 -1607 1G/2G (rs1799750) and MMP3 -1171 5A/6A (rs3025058) polymorphisms were determi ...[more]