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Comparison of A1C and fasting glucose criteria to diagnose diabetes among U.S. adults.

ABSTRACT:

Objective

To compare A1C and fasting glucose for the diagnosis of diabetes among U.S. adults.

Research design and methods

This study included 6,890 adults (> or =20 years of age) from the 1999-2006 National Health and Nutrition Examination Survey without a self-reported history of diabetes who had fasted > or =9 h. A1C > or =6.5% and fasting glucose > or =126 mg/dl were used, separately, to define diabetes.

Results

Overall, 1.8% of U.S. adults had A1C > or =6.5% and fasting glucose > or =126 mg/dl, 0.5% had A1C > or =6.5% and fasting glucose <126 mg/dl, and 1.8% had A1C <6.5% and fasting glucose > or =126 mg/dl. Compared with individuals with A1C <6.5% and fasting glucose > or =126 mg/dl, individuals with A1C > or =6.5% and fasting glucose <126 mg/dl were younger, more likely to be non-Hispanic black, had lower Hb levels, and had higher C-reactive protein.

Conclusions

A1C > or =6.5% demonstrates reasonable agreement with fasting glucose for diagnosing diabetes among U.S. adults.

SUBMITTER: Carson AP

PROVIDER: S-EPMC2797994 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature

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Comparison of A1C and fasting glucose criteria to diagnose diabetes among U.S. adults.

Carson April P AP Reynolds Kristi K Fonseca Vivian A VA Muntner Paul P

Diabetes care 20091006 1

<h4>Objective</h4>To compare A1C and fasting glucose for the diagnosis of diabetes among U.S. adults.<h4>Research design and methods</h4>This study included 6,890 adults (> or =20 years of age) from the 1999-2006 National Health and Nutrition Examination Survey without a self-reported history of diabetes who had fasted > or =9 h. A1C > or =6.5% and fasting glucose > or =126 mg/dl were used, separately, to define diabetes.<h4>Results</h4>Overall, 1.8% of U.S. adults had A1C > or =6.5% and fasting ...[more]

PMID: 19808920

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