Structural studies of the Sputnik virophage.
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ABSTRACT:
SUBMITTER: Sun S
PROVIDER: S-EPMC2798384 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Publications
Structural studies of the Sputnik virophage.
Sun Siyang S La Scola Bernard B Bowman Valorie D VD Ryan Christopher M CM Whitelegge Julian P JP Raoult Didier D Rossmann Michael G MG
Journal of virology 20091104 2
The virophage Sputnik is a satellite virus of the giant mimivirus and is the only satellite virus reported to date whose propagation adversely affects its host virus' production. Genome sequence analysis showed that Sputnik has genes related to viruses infecting all three domains of life. Here, we report structural studies of Sputnik, which show that it is about 740 A in diameter, has a T=27 icosahedral capsid, and has a lipid membrane inside the protein shell. Structural analyses suggest that t ...[more]
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