Ontology highlight
ABSTRACT:
SUBMITTER: Girlich D
PROVIDER: S-EPMC2798510 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Girlich Delphine D Poirel Laurent L Nordmann Patrice P
Antimicrobial agents and chemotherapy 20091109 1
A Pseudomonas fluorescens isolate (PF-1) resistant to carbapenems was recovered during an environmental survey performed with water from the Seine River (Paris). It expressed a novel Ambler class A carbapenemase, BIC-1, sharing 68 and 59% amino acid identities with beta-lactamases SFC-1 from Serratia fonticola and the plasmid-encoded KPC-2, respectively. beta-Lactamase BIC-1 hydrolyzed penicillins, carbapenems, and cephalosporins except ceftazidime and monobactams. The bla(BIC-1) gene was chromo ...[more]