Ontology highlight
ABSTRACT:
SUBMITTER: Mulrooney CA
PROVIDER: S-EPMC2798903 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20100101 1
An enantioselective approach to the perylenequinone core found in the mold perylenequinone natural products is outlined. Specifically, the first asymmetric syntheses of helical chiral perylenequinones absent any additional stereogenic centers are described. Key elements of the synthetic venture include a catalytic enantioselective biaryl coupling, a PIFA-induced naphthalene hydroxylation, and a palladium-mediated aromatic decarboxylation. Transfer of the binaphthalene axial stereochemistry to th ...[more]