Ontology highlight
ABSTRACT:
SUBMITTER: Kose AR
PROVIDER: S-EPMC2799875 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Kose Ayse R AR Fischer Birgit B Mao Leidong L Koser Hur H
Proceedings of the National Academy of Sciences of the United States of America 20091207 51
We present a simple microfluidic platform that uses biocompatible ferrofluids for the controlled manipulation and rapid separation of both microparticles and live cells. This low-cost platform exploits differences in particle size, shape, and elasticity to achieve rapid and efficient separation. Using microspheres, we demonstrate size-based separation with 99% separation efficiency and sub-10-microm resolution in <45 s. We also show continuous manipulation and shape-based separation of live red ...[more]