Ontology highlight
ABSTRACT:
SUBMITTER: MacCallum JL
PROVIDER: S-EPMC2801025 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
MacCallum Justin L JL Hua Lan L Schnieders Michael J MJ Pande Vijay S VS Jacobson Matthew P MP Dill Ken A KA
Proteins 20090101
Here, we summarize the assessment of protein structure refinement in CASP8. Twenty-four groups refined a total of 12 target proteins. Averaging over all groups and all proteins, there was no net improvement over the original starting models. However, there are now some individual research groups who consistently do improve protein structures relative to a starting starting model. We compare various measures of quality assessment, including (i) standard backbone-based methods, (ii) new methods fr ...[more]