Ontology highlight
ABSTRACT:
SUBMITTER: Aksay E
PROVIDER: S-EPMC2803116 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Aksay Emre E Olasagasti Itsaso I Mensh Brett D BD Baker Robert R Goldman Mark S MS Tank David W DW
Nature neuroscience 20070318 4
In neural integrators, transient inputs are accumulated into persistent firing rates that are a neural correlate of short-term memory. Integrators often contain two opposing cell populations that increase and decrease sustained firing as a stored parameter value rises. A leading hypothesis for the mechanism of persistence is positive feedback through mutual inhibition between these opposing populations. We tested predictions of this hypothesis in the goldfish oculomotor velocity-to-position inte ...[more]