Ontology highlight
ABSTRACT:
SUBMITTER: Hofmann AF
PROVIDER: S-EPMC2803226 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Hofmann Alan F AF Hagey Lee R LR Krasowski Matthew D MD
Journal of lipid research 20090728 2
Biliary bile salt composition of 677 vertebrate species (103 fish, 130 reptiles, 271 birds, 173 mammals) was determined. Bile salts were of three types: C(27) bile alcohols, C(27) bile acids, or C(24) bile acids, with default hydroxylation at C-3 and C-7. C(27) bile alcohols dominated in early evolving fish and amphibians; C(27) bile acids, in reptiles and early evolving birds. C(24) bile acids were present in all vertebrate classes, often with C(27) alcohols or with C(27) acids, indicating two ...[more]