Ontology highlight
ABSTRACT:
SUBMITTER: Quintero OA
PROVIDER: S-EPMC2805763 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Quintero Omar A OA DiVito Melinda M MM Adikes Rebecca C RC Kortan Melisa B MB Case Lindsay B LB Lier Audun J AJ Panaretos Niki S NS Slater Stephanie Q SQ Rengarajan Michelle M Feliu Marianela M Cheney Richard E RE
Current biology : CB 20091126 23
Mitochondria are pleomorphic organelles that have central roles in cell physiology. Defects in their localization and dynamics lead to human disease. Myosins are actin-based motors that power processes such as muscle contraction, cytokinesis, and organelle transport. Here we report the initial characterization of myosin-XIX (Myo19), the founding member of a novel class of myosin that associates with mitochondria. The 970 aa heavy chain consists of a motor domain, three IQ motifs, and a short tai ...[more]