Network analyses structure genetic diversity in independent genetic worlds.
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ABSTRACT:
SUBMITTER: Halary S
PROVIDER: S-EPMC2806761 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Publications
Network analyses structure genetic diversity in independent genetic worlds.
Halary Sébastien S Leigh Jessica W JW Cheaib Bachar B Lopez Philippe P Bapteste Eric E
Proceedings of the National Academy of Sciences of the United States of America 20091210 1
DNA flows between chromosomes and mobile elements, following rules that are poorly understood. This limited knowledge is partly explained by the limits of current approaches to study the structure and evolution of genetic diversity. Network analyses of 119,381 homologous DNA families, sampled from 111 cellular genomes and from 165,529 phage, plasmid, and environmental virome sequences, offer challenging insights. Our results support a disconnected yet highly structured network of genetic diversi ...[more]
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