Ontology highlight
ABSTRACT:
SUBMITTER: Raabe R
PROVIDER: S-EPMC2809336 | biostudies-literature | 2008
REPOSITORIES: biostudies-literature
Raabe Richard R Gentile Lisa L
Journal of biophysics (Hindawi Publishing Corporation : Online) 20080605
The targets for tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and selective norepinephrine reuptake inhibitors (SNRIs) are known to be the serotonin and norepinephrine transport (reuptake) proteins which are embedded in presynaptic nerve terminals and function to bring these neurotransmitters from the synaptic cleft back into the presynaptic neuron. Using a combination of intrinsic and extrinsic fluorescence quenching, Stern-Volmer analysis, and protease prot ...[more]