Ontology highlight
ABSTRACT:
SUBMITTER: Frohler S
PROVIDER: S-EPMC2811132 | biostudies-literature | 2009
REPOSITORIES: biostudies-literature
BMC genomics 20091229
<h4>Background</h4>Higher eukaryotes control the expression of their genes by mechanisms that we are just beginning to understand. A complex layer of control is the dynamic spatial organization of the nucleus.<h4>Results</h4>We present a bioinformatics solution (3PD) to support the experimentalist in detecting long-ranging intra or inter chromosomal contacts by Chromosome conformation capture (3C) assays. 3C assays take a snapshot of chromosomal contacts by a fixation step and quantify them by P ...[more]