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Antibodies against structural and nonstructural proteins of human bocavirus in human sera.


ABSTRACT: Immunofluorescence assays (IFAs) for detection of human bocavirus (HBoV) proteins (VP1, VP2, NP-1, and NS1) were developed. The VP1 IFA was the most sensitive for detection of IgG antibody and suitable for screening. IgG antibodies in convalescent-phase sera from HBoV-positive patients were detected by VP1 and VP2 IFAs. Sensitivities of NP-1 and NS1 IFAs were low.

SUBMITTER: Shirkoohi R 

PROVIDER: S-EPMC2812099 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature

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Antibodies against structural and nonstructural proteins of human bocavirus in human sera.

Shirkoohi Reza R   Endo Rika R   Ishiguro Nobuhisa N   Teramoto Shinobu S   Kikuta Hideaki H   Ariga Tadashi T  

Clinical and vaccine immunology : CVI 20091202 1


Immunofluorescence assays (IFAs) for detection of human bocavirus (HBoV) proteins (VP1, VP2, NP-1, and NS1) were developed. The VP1 IFA was the most sensitive for detection of IgG antibody and suitable for screening. IgG antibodies in convalescent-phase sera from HBoV-positive patients were detected by VP1 and VP2 IFAs. Sensitivities of NP-1 and NS1 IFAs were low. ...[more]

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