Ontology highlight
ABSTRACT:
SUBMITTER: Packianathan C
PROVIDER: S-EPMC2812345 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Journal of virology 20091125 3
In infected cells, virus components must be organized at the right place and time to ensure assembly of infectious virions. From a different perspective, assembly must be prevented until all components are available. Hypothetically, this can be achieved by allosterically controlling assembly. Consistent with this hypothesis, here we show that the structure of the hepatitis B virus (HBV) core protein dimer, which can spontaneously self-assemble, is incompatible with capsid assembly. Systematic di ...[more]