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Genome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW).


ABSTRACT: The 3.1-Mb genome of an outbreak methicillin-resistant Staphylococcus aureus (MRSA) strain (TW20) contains evidence of recently acquired DNA, including two large regions (635 kb and 127 kb). The strain is resistant to a wide range of antibiotics, antiseptics, and heavy metals due to resistance genes encoded on mobile genetic elements and also mutations in housekeeping genes.

SUBMITTER: Holden MT 

PROVIDER: S-EPMC2812470 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature

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Genome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW).

Holden Matthew T G MT   Lindsay Jodi A JA   Corton Craig C   Quail Michael A MA   Cockfield Joshua D JD   Pathak Smriti S   Batra Rahul R   Parkhill Julian J   Bentley Stephen D SD   Edgeworth Jonathan D JD  

Journal of bacteriology 20091130 3


The 3.1-Mb genome of an outbreak methicillin-resistant Staphylococcus aureus (MRSA) strain (TW20) contains evidence of recently acquired DNA, including two large regions (635 kb and 127 kb). The strain is resistant to a wide range of antibiotics, antiseptics, and heavy metals due to resistance genes encoded on mobile genetic elements and also mutations in housekeeping genes. ...[more]

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