Ontology highlight
ABSTRACT:
SUBMITTER: Souza-Silva FA
PROVIDER: S-EPMC2813155 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Souza-Silva Flávia A FA da Silva-Nunes Mônica M Sanchez Bruno A M BA Ceravolo Isabela P IP Malafronte Rosely S RS Brito Cristiana F A CF Ferreira Marcelo U MU Carvalho Luzia H LH
The American journal of tropical medicine and hygiene 20100201 2
Duffy binding protein (DBP), a leading malaria vaccine candidate, plays a critical role in Plasmodium vivax erythrocyte invasion. Sixty-eight of 366 (18.6%) subjects had IgG anti-DBP antibodies by enzyme-linked immunosorbent assay (ELISA) in a community-based cross-sectional survey in the Brazilian Amazon Basin. Despite continuous exposure to low-level malaria transmission, the overall seroprevalence decreased to 9.0% when the population was reexamined 12 months later. Antibodies from 16 of 50 ( ...[more]