Ontology highlight
ABSTRACT:
SUBMITTER: Nunez-Iglesias J
PROVIDER: S-EPMC2813862 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Nunez-Iglesias Juan J Liu Chun-Chi CC Morgan Todd E TE Finch Caleb E CE Zhou Xianghong Jasmine XJ
PloS one 20100201 2
Although microRNAs are being extensively studied for their involvement in cancer and development, little is known about their roles in Alzheimer's disease (AD). In this study, we used microarrays for the first joint profiling and analysis of miRNAs and mRNAs expression in brain cortex from AD and age-matched control subjects. These data provided the unique opportunity to study the relationship between miRNA and mRNA expression in normal and AD brains. Using a non-parametric analysis, we showed t ...[more]