Ontology highlight
ABSTRACT:
SUBMITTER: Via LE
PROVIDER: S-EPMC2815586 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Via Laura E LE Cho Sang-Nae SN Hwang Soohee S Bang Hyeeun H Park Seung Kyu SK Kang Hyung Seok HS Jeon Doosoo D Min Seon Yeong SY Oh Taegwon T Kim Yeun Y Kim Young Mi YM Rajan Vignesh V Wong Sharon Y SY Shamputa Isdore Chola IC Carroll Matthew M Goldfeder Lisa L Lee Song A SA Holland Steven M SM Eum Seokyong S Lee Hyeyoung H Barry Clifton E CE
Journal of clinical microbiology 20091223 2
The aminoglycosides streptomycin, amikacin, and kanamycin and the cyclic polypeptide capreomycin are all widely used in second-line therapy for patients who develop multidrug-resistant tuberculosis. We have characterized a set of 106 clinical isolates of Mycobacterium tuberculosis using phenotypic drug susceptibility testing (DST) to determine the extent of resistance to each agent and cross-resistance between agents. These results were compared with polymorphisms in the DNA sequences of ribosom ...[more]