Ontology highlight
ABSTRACT:
SUBMITTER: Charmoy M
PROVIDER: S-EPMC2816696 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Charmoy Mélanie M Brunner-Agten Saskia S Aebischer David D Auderset Floriane F Launois Pascal P Milon Geneviève G Proudfoot Amanda E I AE Tacchini-Cottier Fabienne F
PLoS pathogens 20100205 2
Neutrophils are rapidly and massively recruited to sites of microbial infection, where they can influence the recruitment of dendritic cells. Here, we have analyzed the role of neutrophil released chemokines in the early recruitment of dendritic cells (DCs) in an experimental model of Leishmania major infection. We show in vitro, as well as during infection, that the parasite induced the expression of CCL3 selectively in neutrophils from L. major resistant mice. Neutrophil-secreted CCL3 was crit ...[more]