Ontology highlight
ABSTRACT:
SUBMITTER: Nielsen JS
PROVIDER: S-EPMC2817478 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Nucleic acids research 20091126 3
Small trans-encoded RNAs (sRNAs) modulate the translation and decay of mRNAs in bacteria. In Gram-negative species, antisense regulation by trans-encoded sRNAs relies on the Sm-like protein Hfq. In contrast to this, Hfq is dispensable for sRNA-mediated riboregulation in the Gram-positive species studied thus far. Here, we provide evidence for Hfq-dependent translational repression in the Gram-positive human pathogen Listeria monocytogenes, which is known to encode at least 50 sRNAs. We show that ...[more]