Ontology highlight
ABSTRACT:
SUBMITTER: Whittaker JW
PROVIDER: S-EPMC2818121 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Biochimica et biophysica acta 20090820 2
Manganese superoxide dismutase is an important antioxidant defense metalloenzyme that protects cells from damage by the toxic oxygen metabolite, superoxide free radical, formed as an unavoidable by-product of aerobic metabolism. Many years of research have gone into understanding how the metal cofactor interacts with small molecules in its catalytic role. In contrast, very little is presently known about how the protein acquires its metal cofactor, an important step in the maturation of the prot ...[more]