Ontology highlight
ABSTRACT:
SUBMITTER: Macaubas C
PROVIDER: S-EPMC2818241 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Macaubas Claudia C Nguyen Khoa K Deshpande Chetan C Phillips Carolyn C Peck Ariana A Lee Tzielan T Park Jane L JL Sandborg Christy C Mellins Elizabeth D ED
Clinical immunology (Orlando, Fla.) 20091029 2
Juvenile idiopathic arthritis (JIA) encompasses a group of chronic childhood arthritides of unknown etiology. One subtype, systemic JIA (SJIA), is characterized by a combination of arthritis and systemic inflammation. Its systemic nature suggests that clues to SJIA pathogenesis may be found in examination of peripheral blood cells. To determine the immunophenotypic profiles of circulating mononuclear cells in SJIA patients with different degrees of disease activity, we studied PBMC from 31 SJIA ...[more]