Ontology highlight
ABSTRACT:
SUBMITTER: Holland GP
PROVIDER: S-EPMC2818250 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Journal of magnetic resonance (San Diego, Calif. : 1997) 20091004 1
In this article, we show the potential for utilizing proton-detected heteronuclear single quantum correlation (HSQC) NMR in rigid solids under ultra-fast magic angle spinning (MAS) conditions. The indirect detection of carbon-13 from coupled neighboring hydrogen nuclei provides a sensitivity enhancement of 3- to 4-fold in crystalline amino acids over direct-detected versions. Furthermore, the sensitivity enhancement is shown to be significantly larger for disordered solids that display inhomogen ...[more]