Ontology highlight
ABSTRACT:
SUBMITTER: Stern E
PROVIDER: S-EPMC2818341 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Stern Eric E Vacic Aleksandar A Rajan Nitin K NK Criscione Jason M JM Park Jason J Ilic Bojan R BR Mooney David J DJ Reed Mark A MA Fahmy Tarek M TM
Nature nanotechnology 20091213 2
Label-free nanosensors can detect disease markers to provide point-of-care diagnosis that is low-cost, rapid, specific and sensitive. However, detecting these biomarkers in physiological fluid samples is difficult because of problems such as biofouling and non-specific binding, and the resulting need to use purified buffers greatly reduces the clinical relevance of these sensors. Here, we overcome this limitation by using distinct components within the sensor to perform purification and detectio ...[more]