Ontology highlight
ABSTRACT:
SUBMITTER: Carbon M
PROVIDER: S-EPMC2818462 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Neurobiology of disease 20091110 2
Impairment of sequence learning is common in Parkinson's disease (PD), but the time course of this cognitive abnormality is not known. We assessed longitudinal changes in sequence learning performance and associated task-related cerebral blood flow in 13 early stage PD patients who underwent H(2)(15)O PET at baseline and again 2 years later. Ten healthy volunteer subjects served as controls. A trend toward decline in learning performance (p=0.08) was evident over the 2 years of follow-up. During ...[more]