Ontology highlight
ABSTRACT:
SUBMITTER: Hicks SW
PROVIDER: S-EPMC2822022 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Hicks Stuart W SW Galán Jorge E JE
Current opinion in microbiology 20091228 1
Ubiquitinylation of proteins is a critical mechanism in regulating numerous eukaryotic cellular processes including cell cycle progression, inflammatory response, and vesicular trafficking. Given the importance of ubiquitinylation, it is not surprising that several pathogenic bacteria have developed strategies to exploit various stages of the ubiquitin pathway for their own benefit. One such strategy is the delivery of bacterial 'effector' proteins into the host cell cytosol, which mimic the act ...[more]