Ontology highlight
ABSTRACT:
SUBMITTER: Yap VB
PROVIDER: S-EPMC2822286 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Molecular biology and evolution 20091008 3
Analysis of natural selection is key to understanding many core biological processes, including the emergence of competition, cooperation, and complexity, and has important applications in the targeted development of vaccines. Selection is hard to observe directly but can be inferred from molecular sequence variation. For protein-coding nucleotide sequences, the ratio of nonsynonymous to synonymous substitutions (omega) distinguishes neutrally evolving sequences (omega = 1) from those subjected ...[more]