The role of pharmacogenomics in improving the management of asthma.
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ABSTRACT:
SUBMITTER: Kazani S
PROVIDER: S-EPMC2824610 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Publications
The role of pharmacogenomics in improving the management of asthma.
Kazani Shamsah S Wechsler Michael E ME Israel Elliot E
The Journal of allergy and clinical immunology 20100201 2
There is a large amount of interindividual variability in both therapeutic and adverse responses to asthma therapies. Genetic variability can account for 50% to 60% of this variability. Pharmacogenomics holds out the promise of allowing clinicians to prospectively choose therapies that have the greatest likelihood to be effective for individual patients and to avoid those that might have a high likelihood of producing adverse effects. In this article we review the principles of pharmacogenomic i ...[more]
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