Ontology highlight
ABSTRACT:
SUBMITTER: Sood A
PROVIDER: S-EPMC2825098 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Sood Amit A Ebbert Jon O JO Wyatt Kirk D KD Croghan Ivana T IT Schroeder Darrell R DR Sood Richa R Hays J Taylor JT
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20100115 3
<h4>Introduction</h4>We conducted a preliminary proof-of-concept study evaluating gabapentin for the treatment of tobacco dependence.<h4>Methods</h4>Subjects (N = 80) were randomized to gabapentin (600 mg three times per day or 900 mg three times per day) or placebo. After a 2-week dose titration, the target dose was maintained for 9 weeks and then tapered over 1 week. Follow-up was for 12 weeks after the medication phase.<h4>Results</h4>The study had high dropout rates with more than one half o ...[more]