Functional consequences of animal-to-animal variation in circuit parameters.
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ABSTRACT:
SUBMITTER: Goaillard JM
PROVIDER: S-EPMC2826985 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Publications
Functional consequences of animal-to-animal variation in circuit parameters.
Goaillard Jean-Marc JM Taylor Adam L AL Schulz David J DJ Marder Eve E
Nature neuroscience 20091018 11
How different are the neuronal circuits for a given behavior across individual animals? To address this question, we measured multiple cellular and synaptic parameters in individual preparations to see how they correlated with circuit function, using neurons and synapses in the pyloric circuit of the stomatogastric ganglion of the crab Cancer borealis. There was considerable preparation-to-preparation variability in the strength of two identified synapses, in the amplitude of a modulator-evoked ...[more]
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