Ontology highlight
ABSTRACT:
SUBMITTER: Li H
PROVIDER: S-EPMC2828108 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Bioinformatics (Oxford, England) 20100115 5
<h4>Motivation</h4>Many programs for aligning short sequencing reads to a reference genome have been developed in the last 2 years. Most of them are very efficient for short reads but inefficient or not applicable for reads >200 bp because the algorithms are heavily and specifically tuned for short queries with low sequencing error rate. However, some sequencing platforms already produce longer reads and others are expected to become available soon. For longer reads, hashing-based software such ...[more]