Ontology highlight
ABSTRACT:
SUBMITTER: Roberts RK
PROVIDER: S-EPMC2829461 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Roberts Randolph K RK Appel Bruce B
Developmental dynamics : an official publication of the American Association of Anatomists 20090701 7
During development, neural precursors divide to produce new precursors and cells that differentiate as neurons and glia. In Drosophila, apicobasal polarity and orientation of the mitotic spindle play important roles in specifying the progeny of neural precursors for different fates. We examined orientation of zebrafish spinal cord precursors using time-lapse imaging and tested the function of protein kinase C, iota (PrkCi), a member of the Par complex of proteins necessary for apicobasal polarit ...[more]