Dataset Information

Incorporating mortality risk into estimates of 5-year glaucoma risk.

ABSTRACT:

Purpose

To incorporate mortality risk, a potentially important factor to consider when deciding whether to initiate therapy for ocular hypertensives, into estimates of 5-year glaucoma risk.

Design

Comparison study of estimates of glaucoma risk that do and do not account for mortality risk.

Methods

We computed 5-year risk of glaucoma for a set of hypothetical glaucoma suspects. We then determined their 5-year risk of death using the Charlson index, which is based on age and comorbidity, and computed mortality-adjusted 5-year risk that the individual will develop glaucoma before death.

Results

Accounting for mortality risk reduces the risk of developing glaucoma in one's lifetime. For example, a 75-year-old patient with an unadjusted 5-year glaucoma risk of 51.0% can have mortality-adjusted 5-year glaucoma risks of 41.8% (18% relative risk reduction) or 20.2% (60% relative risk reduction) assuming the patient has a Charlson comorbidity score of 1 or 3, respectively.

Conclusions

Shortened life expectancy reduces 5-year risk of developing glaucoma. Thus, mortality risk is another factor clinicians should consider when deciding whether to initiate treatment of glaucoma suspects.

SUBMITTER: Griffin BA

PROVIDER: S-EPMC2830147 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature

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Publications

Incorporating mortality risk into estimates of 5-year glaucoma risk.

Griffin Beth Ann BA Elliott Marc N MN Coleman Anne L AL Cheng Eric M EM

American journal of ophthalmology 20091002 6

<h4>Purpose</h4>To incorporate mortality risk, a potentially important factor to consider when deciding whether to initiate therapy for ocular hypertensives, into estimates of 5-year glaucoma risk.<h4>Design</h4>Comparison study of estimates of glaucoma risk that do and do not account for mortality risk.<h4>Methods</h4>We computed 5-year risk of glaucoma for a set of hypothetical glaucoma suspects. We then determined their 5-year risk of death using the Charlson index, which is based on age and ...[more]

PMID: 19800612

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Dataset Information

Incorporating mortality risk into estimates of 5-year glaucoma risk.

Purpose

Design

Methods

Results

Conclusions

Publications

Incorporating mortality risk into estimates of 5-year glaucoma risk.

Similar Datasets

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